Familial glioblastoma.
نویسندگان
چکیده
The authors describe a family with three members affected by glioblastoma. The proband patient, a 7 year-old girl, developed a rare complication, a pulmonary metastasis. Chromosomal analysis of her peripheral blood lymphocytes showed a normal karyotype (46, XX), without structural abnormalities. Cytogenetic study of the tumor cells disclosed several abnormalities: 46, XX, 7q-/46, XX, -2, 4p-, 7p-, +15/46, XX. Some aspects about genetics of glial neoplasms are discussed.
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ورودعنوان ژورنال:
- Arquivos de neuro-psiquiatria
دوره 53 2 شماره
صفحات -
تاریخ انتشار 1995